Rege-Jean Page - The actor skyrocketed to fame after Bridgerton became the most-watched series in Netflix’s history. However, he opted not to return for season 2.
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Gavin Leatherwood: The actor appeared in all but one episode of HBO Max's The Sex Lives of College Girls season 1, but he decided not to return as Kimberly's (Pauline Chalamet) love interest, Nico Murray in season 2.
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Lauren Graham: The Gilmore Girls alum exited Zoey’s Extraordinary Playlist during the show’s season 2 premiere in January 2021. Graham played Joan, Zoey Clarke’s (Jane Levy) boss throughout the first season of the NBC series.
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Anna Faris exited CBS' Mom in September 2020 after leading the show for seven seasons alongside Allison Janney.
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Ruby Rose: Batwoman fans were shocked at the end of season 1 when Rose announced that she would not be returning for future seasons
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Justin Chambers: The actor shocked Grey’s Anatomy fans in January 2020 when he announced he was leaving the long-running medical drama after 16 seasons.